Malondialdehyde-Like Material and Beta-Thromboglobulin Plasma Levels in Patients Suffering From Transient Ischemic Attacks
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چکیده
Controlled trial of aspirin in cerebral ischemia. Circulation 62(supp V): V-90-96, 1980 22. Bousser MG, Eschwege E, Haguenau M, et al: "AICLA" controlled trial of aspirin and dipyridamole in the secondary prevention of atherothrombotic cerebral ischemia. Stroke 14: 5-14, 1983 23. Kelton JG, Carter CJ, Rosenfeld J, Massicotte-Nolan MP, Hirsh J: Sex-related differences in the efficacy of acetylsalicylic acid (ASA): The absorption of ASA and its effect on collagen-induced thromboxane B2 generation. Thrombosis Research 24: 163-168, 1981 24. Patrignani P, Filabozzi P, Patrono C: Selective cumulative inhibition of platelet thromboxane production by low-dose aspirin in healthy subjects. J Clin Invest 69: 1366-1372 25. Barnett HJM, McDonald JWD, Sackett DL: Aspirin — effective in males threatened with stroke. Stroke 9: 295-298, 1978 26. Abdel-Halim M, Von Hoist H, Myerson B, et al. Prostaglandin profiles in tissue and blood vessels from human brain. J Neurochem34: 1331-1333, 1980
منابع مشابه
Malondialdehyde-like material and beta-thromboglobulin plasma levels in patients suffering from transient ischemic attacks.
Beta-thromboglobulin (betaTG) and malondialdehyde-like material (MDA-LM) plasma levels were studied in patients affected by transient ischemic attacks (TIA) after 2-4 months from the last episode. BetaTG and MDA-LM values were significantly higher in TIA patients than in 20 controls matched for age. No correlation between MDA-LM and betaTG was seen. This study suggests that in vivo platelet act...
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We studied the effect of acetylsalicylic acid (ASA) versus placebo on B-thromboglobulin (B-TG) and platelet factor 4 (PF4) plasma levels and ADP-induced platelet aggregation in 25 male patients with transient ischaemic attacks (TIA). The patients were allocated randomly to two groups: 14 patients received oral treatment with ASA 500 mg b.i.d. for 14 days, 11 patients placebo b.i.d. for the same...
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Plasma malondialdehyde-like material (MDA-LM) was evaluated in 138 normal subjects and in a group of 57 stroke patients using a modification of the method of Smith et al. (1976). The basal level of MDA-LM in the control group was 35 mumol/l with a range of 22-50 mumol/l. Values above 50 mumol/l were found in 80% of the patients suffering from subarachnoid haemorrhage, in 68% of those with cereb...
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It remains uncertain whether platelet activation in ischemic stroke is contributory or secondary to brain ischemia. The efficacy of aspirin (ASA) in stroke prevention suggests that platelet activation contributes to the occurrence of stroke. On the other hand, platelet activation may be simply a generalized consequence of cerebral ischemic damage. To examine this issue, plasma levels of the pla...
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